Mechanics of Biological Tissues
The structure-function relationships of biological materials are critical to understating tissue development, function, disease, and therapy. We use custom-built devices to simultaneously study structure and mechanics of biological tissues.
3D imaging and mechanical modeling of helical buckling in Medicago truncatula plant roots
Localization of Viscous Behavior and Shear Energy Dissipation in Articular Cartilage Under Dynamic Shear Loading
Anatomic variation of depth-dependent mechanical properties in neonatal bovine articular cartilage
Spatial periodicity in growth plate shear mechanical properties is disrupted by vitamin D deficiency
Effects of Enzymatic Treatments on the Depth-Dependent Viscoelastic Shear Properties of Articular Cartilage
Plant Root Buckling in a Stiff Gel
Plant Root Buckling in a Soft Gel
Compliant regions in cartilage
Fluorescence movie of human knee cartilage under shear. The cartilage is stained green, then photobleached, to allow for calculation of strains and displacements, and in turn for calculations of local moduli. Notice that the upper region, close to the articular surface, is much more compliant than the bulk.
Time lapse video of Medicago root growing.
Time lapse video of the front view of a Medicago root growing on an inclined plane within a gel. One photo is taken an hour over a course of 2 weeks. Note the root waving as it hits the glass plane.